ea0085p25 | Gonadal, DSD and Reproduction | BSPED2022
Jones Lily
, Blair Joanne
, Park Julie
, Dliso Silothabo
, Hawcutt Daniel
, YH Lip Gregory
, Shantsila Alena
Background: Increased hair cortisol concentrations are reported in Turner Syndrome (TS) patients compared to healthy controls (HC).(1) Increased cortisol exposure could contribute to cardiovascular, metabolic and bone morbidity in TS. Hair cortisol concentrations give no information about the circadian profile of cortisol, which is important for cardiovascular health. Cortisol is inactivated to cortisone by 11β hydroxysteroid dehydrogenase (11βHSD) type-2 and regener...